Built on Science, Not Trends
Women in midlife deserve targeted, evidence-informed formulas that support strength, metabolic health, and long-term vitality. As our bodies change with age, the nutrients we rely on also change — which is why ByEla™ delivers well-studied ingredients at clinically-grade dosages to support muscle, bone, and cognitive systems.
Midlife Changes the Body’s Rules
As estrogen levels shift with age, many women experience differences in energy metabolism, recovery, bone density, and muscle maintenance. Research suggests that targeted nutritional support, particularly when paired with strength training, can help support stronger muscles, denser bones, and sharper cognitive function well into later decades.
These findings are backed by human clinical research on the nutrients included in Creatine+.
Why Strength Matters More After 40
Cardio supports heart health. Strength training preserves muscle, bone, and metabolic function — all of which become increasingly important in midlife. Beyond aesthetics, strength supports daily function, physical resilience, and long-term independence.
Creatine+ was designed to support women who lift, train, and move with intention, because strength is the foundation of longevity.
Creatine when combined with resistance training is proven to support:
Cognitive Function +
Brain fog, mental fatigue, and reduced focus are common during perimenopause. Creatine supports brain energy metabolism and has been studied for its role in cognitive performance and mental clarity during periods of hormonal change and aging.*
Recovery After Physical Activity +
Recovery can take longer in midlife. Creatine supports energy replenishment after exercise, which may help reduce fatigue and support better readiness for your next workout or active day.*
Lean Muscle +
As estrogen levels shift in perimenopause, the body becomes less efficient at maintaining muscle. Creatine supports lean muscle when paired with resistance training, helping counter age-related muscle loss and supporting strength over time.*
Exercise Performance +
Many women notice workouts start to feel harder during perimenopause. Creatine supports strength and power during training, helping you feel more capable, consistent, and confident in your workouts.*
Why Creatine+ Is Built for Women 40+
Because muscle is longevity.
Women lose up to 8% of muscle per decade after 40—and up to 20% after menopause. Supporting muscle through resistance training and nutrition is one of the most effective ways to protect strength, mobility, and bone density long-term.
Because hormones shift everything.
Changes in estrogen affect energy, recovery, thermoregulation, bone density, mental clarity, immune system function, and mood. Creatine+ aligns with the systems that need the most support during this transition.
Because simplicity matters.
Creatine+ brings together research-backed ingredients that support muscle health (alongside resistance training), bone strength, cognitive function, and energy levels—all in one convenient daily ritual designed for women who want comprehensive wellness solutions. One simple scoop replaces a stack of 20+ supplements, without sacrificing quality or results.
Clinical Studies & Sources
Creatine
Effects of an 8-week creatine hydrochloride supplementation protocol on cognitive function, brain creatine concentrations, and clinical outcomes in perimenopausal and postmenopausal women. Journal Name. PubMed ID 40854087. 2025 https://pubmed.ncbi.nlm.nih.gov/40854087/
A two-year randomized controlled trial on creatine monohydrate supplementation and exercise for bone health in postmenopausal women. Medicine & Science in Sports & Exercise. 2023 https://pmc.ncbi.nlm.nih.gov/articles/PMC10487398/
Creatine supplementation in women’s health: a lifespan perspective. Nutrients, 13 (3), 877. 2021 https://pmc.ncbi.nlm.nih.gov/articles/PMC7998865/
Calcium
Calcium Intake and Bone Mineral Density: A Systematic Review and Meta-Analysis BMJ, 2015. https://pubmed.ncbi.nlm.nih.gov/26420598/
Vitamin D3 & K2
The Synergistic Interplay Between Vitamins D and K for Bone and Cardiovascular Health: A Narrative Review International Journal of Endocrinology, 2017. https://pmc.ncbi.nlm.nih.gov/articles/PMC5613455/
Citicoline
Effects of Citicoline (CDP-Choline) on Memory Function in Healthy Older Adults The Journal of Nutrition, 2021 https://pmc.ncbi.nlm.nih.gov/articles/PMC8349115/
Ashwagandha
Current Research on the Health-Promoting Activities of Ashwagandha (Withania somnifera): A Narrative Review Pharmaceutics, 2023 https://pmc.ncbi.nlm.nih.gov/articles/PMC10147008/
Maca Root
A systematic review of the versatile effects of Peruvian Maca root (Lepidium meyenii) on sexual dysfunction, menopausal symptoms, and related conditions. Phytomedicine Plus. 2022 https://www.sciencedirect.com/science/article/pii/S2667031322001075
Magnesium
Effects of magnesium supplementation on muscle soreness in different types of physical activities: A systematic review. Journal of Translational Medicine. 2024 https://pmc.ncbi.nlm.nih.gov/articles/PMC11227245/
L-Theanine
Effects of L-theanine administration on stress-related symptoms and cognitive functions in healthy adults: A randomized, placebo-controlled trial. Nutrients. 2019 https://pmc.ncbi.nlm.nih.gov/articles/PMC6836118/
Vitamin C
Vitamin C — Health Professional Fact Sheet National Institutes of Health, Office of Dietary Supplements, 2025 https://ods.od.nih.gov/factsheets/VitaminC-HealthProfessional/
Vitamin B Complex
Dietary vitamin B complex: Orchestration in human nutrition throughout life with sex differences. Nutrients. 2022 https://pmc.ncbi.nlm.nih.gov/articles/PMC9573099/
Zinc
Effectiveness of Eight-Week Zinc Supplementation on Vitamin D₃ Status and Leptin Levels in Postmenopausal Women. Journal of Trace Elements in Medicine and Biology, 2021 https://www.sciencedirect.com/science/article/pii/S0946672X21000201